Antioxidant therapy for male subfertility: myth or evidence-based?
نویسندگان
چکیده
Muhammad Elmussareh,MRCS, Specialist Registrar in Urology; Ahmed Mahrous, FRCS(Urol), Urology Fellow; Oliver Kayes, FRCS(Urol), Consultant Urologist, St James’s University Hospital, Leeds Around 15% of couples experience infertility, with up to 50% of these related to male factors. Oxidative stress caused by reactive oxygen species, including oxygen ions, free radicals and peroxides, has been reported to play a role in around half of all infertile men. These reactive oxygen species can, when present in high concentrations, damage the sperm membrane in addition to directly damaging the sperm DNA (Figure 1).1
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